DNA alkylator
Inhibitory Selectivity
Isoform-specific Inhibitors
DNA alkylator Products
Catalog No. | Information | Product Use Citations | Product Validations |
---|---|---|---|
S4447 |
PipobromanPipobroman (PB, Vercyte), a neutral amide of piperazine, acts as an alkylating agent with antiproliferative activity. |
||
S6958 |
TreosulfanTreosulfan (NSC 39069, Treosulphan) is an alkylating agent used for conventional and high-dose chemotherapy regimens. Treosulfan is potently cytotoxic against pancreatic cancer cell lines. |
||
S6984 |
Dianhydrogalactitol (VAL-083)Dianhydrogalactitol (VAL-083, Dianhydrodulcitol, Dulcitol Diepoxide) is a bi-functional alkylating agent that readily crosses the blood-brain barrier and creates N7 methylation on DNA. Dianhydrogalactitol shows antitumor activity. |
||
E0609New |
Methyl methanesulfonateMethyl methanesulfonate (MMS), a DNA alkylating agent, modifies both guanine (to 7-methylguanine) and adenine (to 3-methlyladenine) to cause base mispairing and replication blocks, respectively. |
Catalog No. | Information | Product Use Citations | Product Validations |
---|---|---|---|
S4447 |
PipobromanPipobroman (PB, Vercyte), a neutral amide of piperazine, acts as an alkylating agent with antiproliferative activity. |
||
S6958 |
TreosulfanTreosulfan (NSC 39069, Treosulphan) is an alkylating agent used for conventional and high-dose chemotherapy regimens. Treosulfan is potently cytotoxic against pancreatic cancer cell lines. |
Catalog No. | Information | Product Use Citations | Product Validations |
---|---|---|---|
S6984 |
Dianhydrogalactitol (VAL-083)Dianhydrogalactitol (VAL-083, Dianhydrodulcitol, Dulcitol Diepoxide) is a bi-functional alkylating agent that readily crosses the blood-brain barrier and creates N7 methylation on DNA. Dianhydrogalactitol shows antitumor activity. |
||
E0609New |
Methyl methanesulfonateMethyl methanesulfonate (MMS), a DNA alkylating agent, modifies both guanine (to 7-methylguanine) and adenine (to 3-methlyladenine) to cause base mispairing and replication blocks, respectively. |