GPCR19
Inhibitory Selectivity
GPCR19 Products
Catalog No. | Information | Product Use Citations | Product Validations |
---|---|---|---|
S3069 |
Deoxycholic acid sodium saltDeoxycholic acid sodium salt (Sodium Deoxycholate, Sodium Desoxycholate, Cholanoic Acid, ATX-101, Kythera, Belkyra, DCA) is specifically responsible for activating the TGR5 receptor (GPCR19) that stimulates brown adipose tissue (BAT) thermogenic activity. |
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S6806 |
SBI-115SBI-115 is a novel TGR5 (GPCR19) antagonist. SBI-115 decreases cell proliferation, cholangiocyte spheroid growth and cAMP levels in cystic cholangiocytes. |
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S0034 |
BAR501BAR501 is a potent and selective G protein-coupled bile acid receptor 1 (GPBAR1, GPCR19, TGR5) agonist that effectively transactivates GPBAR1 in HEK293 cells overexpressing a CRE along with GPBAR1 with EC50 of 1 μM. |
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S0193 |
TGR5 Receptor AgonistTGR5 Receptor Agonist (TGR5, CCDC, MDK00245, compd 6) is a potent agonist of TGR5(GPCR19, GPBAR1, M-BAR). TGR5 Receptor Agonist shows improved potency with pEC50 of 6.8 and 7.5 in the U2-OS cell assay and in melanophore cells, respectively. |
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S6741 |
SB-756050SB-756050 is a selective TGR5 agonist (EC50 = 1.3 μM for the human receptor). |
Catalog No. | Information | Product Use Citations | Product Validations |
---|---|---|---|
S3069 |
Deoxycholic acid sodium saltDeoxycholic acid sodium salt (Sodium Deoxycholate, Sodium Desoxycholate, Cholanoic Acid, ATX-101, Kythera, Belkyra, DCA) is specifically responsible for activating the TGR5 receptor (GPCR19) that stimulates brown adipose tissue (BAT) thermogenic activity. |
Catalog No. | Information | Product Use Citations | Product Validations |
---|---|---|---|
S6806 |
SBI-115SBI-115 is a novel TGR5 (GPCR19) antagonist. SBI-115 decreases cell proliferation, cholangiocyte spheroid growth and cAMP levels in cystic cholangiocytes. |
Catalog No. | Information | Product Use Citations | Product Validations |
---|---|---|---|
S0034 |
BAR501BAR501 is a potent and selective G protein-coupled bile acid receptor 1 (GPBAR1, GPCR19, TGR5) agonist that effectively transactivates GPBAR1 in HEK293 cells overexpressing a CRE along with GPBAR1 with EC50 of 1 μM. |
||
S0193 |
TGR5 Receptor AgonistTGR5 Receptor Agonist (TGR5, CCDC, MDK00245, compd 6) is a potent agonist of TGR5(GPCR19, GPBAR1, M-BAR). TGR5 Receptor Agonist shows improved potency with pEC50 of 6.8 and 7.5 in the U2-OS cell assay and in melanophore cells, respectively. |
||
S6741 |
SB-756050SB-756050 is a selective TGR5 agonist (EC50 = 1.3 μM for the human receptor). |