NMDAR

Inhibitory Selectivity

Isoform-specific Inhibitors

NMDAR Products

New NMDAR Products
Catalog No. Information Product Use Citations Product Validations
S6644

Radiprodil (RGH-896)

Radiprodil (RGH-896) is a NR2B-selective NMDA receptor antagonist, initially developed for the treatment of neuropathic pain.

S0446

TCN 201

TCN-201 is a selective GluN1/GluN2A (NR1/NR2A) NMDA receptor antagonist with pIC50 6.8 for NR1/NR2A and <4.3 for NR1/NR2B (GluN1/GluN2B),respectively.

S6907New

Rapastinel (GLYX-13)

Rapastinel (GLYX-13, BV-102, TPPT-amide) is a partial agonist of N-methyl-D-aspartate receptor (NMDAR) that targeting a glycine site. Rapastinel has long-lasting antidepressant effects.

S3203

D-Alanine

D-alanine (Ala, (R)-Alanine, Ba 2776, D-α-Alanine, NSC 158286) is an endogenous co-agonist at the glycine site of the N-methyl-d-aspartate (NMDA) receptor.

S9271

Pulchinenoside A

Pulchinenoside A (Anemoside A3), a natural triterpenoid saponin, is a AMPARs and NMDAR modulator.

Catalog No. Information Product Use Citations Product Validations
S6644

Radiprodil (RGH-896)

Radiprodil (RGH-896) is a NR2B-selective NMDA receptor antagonist, initially developed for the treatment of neuropathic pain.

S0446

TCN 201

TCN-201 is a selective GluN1/GluN2A (NR1/NR2A) NMDA receptor antagonist with pIC50 6.8 for NR1/NR2A and <4.3 for NR1/NR2B (GluN1/GluN2B),respectively.

Catalog No. Information Product Use Citations Product Validations
S6907New

Rapastinel (GLYX-13)

Rapastinel (GLYX-13, BV-102, TPPT-amide) is a partial agonist of N-methyl-D-aspartate receptor (NMDAR) that targeting a glycine site. Rapastinel has long-lasting antidepressant effects.

S3203

D-Alanine

D-alanine (Ala, (R)-Alanine, Ba 2776, D-α-Alanine, NSC 158286) is an endogenous co-agonist at the glycine site of the N-methyl-d-aspartate (NMDA) receptor.

Catalog No. Information Product Use Citations Product Validations
S9271

Pulchinenoside A

Pulchinenoside A (Anemoside A3), a natural triterpenoid saponin, is a AMPARs and NMDAR modulator.