NPY receptor
Inhibitory Selectivity
Isoform-specific Inhibitors
NPY receptor Products
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S0124 |
CGP71683 hydrochlorideCGP71683 hydrochloride (CGP71683A) is a competitive and sellective neuropeptide Y receptor type 5 (Y5 receptor) antagonist with Ki of 1.3 nM. |
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| S6416 |
JNJ 31020028JNJ 31020028 is a novel neuropeptide Y Y2 receptor antagonist which bound with high affinity with human and rat Y2 receptor (pIC50=8.07±0.05 for human Y2 receptor, and pIC50=8.22±0.06 for rat Y2 receptor) and >100-fold selective versus human Y1, Y4, and Y5 receptors. |
||
| E0014New |
BIBO 3304 TrifluoroacetateBIBO 3304 Trifluoroacetate (BIBO-3304 TFA) is a novel neuropeptide Y Y1 receptor (NPY1R) antagonist with IC50 values of 0.38 nM and 0.72 nM for human Y1 receptor and rat Y1 receptor, respectively. BIBO 3304 shows low affinity for the human Y2 receptor, human and rat Y4 receptor as well as for the human and rat Y5 receptor (IC50 values >1000 nM). |
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S0124 |
CGP71683 hydrochlorideCGP71683 hydrochloride (CGP71683A) is a competitive and sellective neuropeptide Y receptor type 5 (Y5 receptor) antagonist with Ki of 1.3 nM. |
||
| S6416 |
JNJ 31020028JNJ 31020028 is a novel neuropeptide Y Y2 receptor antagonist which bound with high affinity with human and rat Y2 receptor (pIC50=8.07±0.05 for human Y2 receptor, and pIC50=8.22±0.06 for rat Y2 receptor) and >100-fold selective versus human Y1, Y4, and Y5 receptors. |
||
| E0014New |
BIBO 3304 TrifluoroacetateBIBO 3304 Trifluoroacetate (BIBO-3304 TFA) is a novel neuropeptide Y Y1 receptor (NPY1R) antagonist with IC50 values of 0.38 nM and 0.72 nM for human Y1 receptor and rat Y1 receptor, respectively. BIBO 3304 shows low affinity for the human Y2 receptor, human and rat Y4 receptor as well as for the human and rat Y5 receptor (IC50 values >1000 nM). |
