Aminopeptidase

Inhibitory Selectivity

Aminopeptidase Products

Catalog No. Information Product Use Citations Product Validations
S1522

Tosedostat (CHR2797)

Tosedostat (CHR2797) is an aminopeptidase inhibitor for LAP, PuSA and Aminopeptidase N with IC50 of 100 nM, 150 nM and 220 nM, respectively, and does not effectively inhibit either PILSAP, MetAP-2, LTA4 hydrolase, or MetAP-2. Phase 2.
PLoS One, 2018, 13(1):e0190682
Integr Biol, 2014, 6(2):164-74
Anal Chem, 2013, 85(10):4991-7
S9631

Puromycin aminonucleoside

Puromycin aminonucleoside (NSC 3056, PAN, Stylomycin aminonucleoside, ARDMA, SAN), the aminonucleoside portion of the antibiotic puromycin, is a reversible inhibitor of dipeptidyl-peptidase II and cytosol alanyl aminopeptidase that induces apoptosis in mesangial cells (MCs) accompanied by declined cell viability and enhanced inflammatory response.
Catalog No. Information Product Use Citations Product Validations
S1522

Tosedostat (CHR2797)

Tosedostat (CHR2797) is an aminopeptidase inhibitor for LAP, PuSA and Aminopeptidase N with IC50 of 100 nM, 150 nM and 220 nM, respectively, and does not effectively inhibit either PILSAP, MetAP-2, LTA4 hydrolase, or MetAP-2. Phase 2.
PLoS One, 2018, 13(1):e0190682
Integr Biol, 2014, 6(2):164-74
Anal Chem, 2013, 85(10):4991-7
S9631

Puromycin aminonucleoside

Puromycin aminonucleoside (NSC 3056, PAN, Stylomycin aminonucleoside, ARDMA, SAN), the aminonucleoside portion of the antibiotic puromycin, is a reversible inhibitor of dipeptidyl-peptidase II and cytosol alanyl aminopeptidase that induces apoptosis in mesangial cells (MCs) accompanied by declined cell viability and enhanced inflammatory response.