Antibiotics
Inhibitory Selectivity
Antibiotics Products
Catalog No. | Information | Product Use Citations | Product Validations |
---|---|---|---|
S7046 |
Brefeldin ABrefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells, induces cancer cell differentiation and apoptosis. It could also improve the HDR(homology-directed repair) efficiency and be an enhancer of CRISPR-mediated HDR. Brefeldin A is also an inhibitor of autophagy and mitophagy. |
![]() ![]() Cells were treated with brefeldin A or manumycin A, and the resulting supernatant was collected after 48 h for exosomal preparation (lanes 1 and 2), or exosomes obtained from C81 cells were trypsin-treated or freeze/thawed (F/T) and then trypsin-treated (lanes 3 and 4). Lanes 5 and 6, input exosome controls from C81 or CEM cells, respectively. Resulting exosomes were assayed for the presence of Tax by Western blotting. |
|
S4974 |
Oxacillin sodiumOxacillin sodium (salt) is a narrow-spectrum β-lactam antibiotic that can be used for treatment of methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia. |
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S5199 |
Oxytetracycline hydrochlorideOxytetracycline (OTC, Oxycycin, Stevacin, Terramycin) hydrochloride is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins. |
||
S4490 |
TetracyclineTetracycline (TC) is a broad-spectrum antibiotic that exhibits activity against a wide range of microorganisms including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, rickettsiae, and protozoan parasites. |
||
S4979 |
Procaine penicillin GPenicillin G Procaine (PGP, Penicillin G Procaine, Bicillin C-R), a crystalline complex combining penicillin G with procaine, is a β-lactam antibiotic. |
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E0706New |
Gemifloxacin mesylateGemifloxacin mesylate (SB265805 mesylate; LB20304 mesylate) is a novel fluoronaphthyridone with a broad spectrum of antimicrobial activity and enhances activity against gram-positive aerobes. |
||
E0656New |
7-Methylcoumarin7-Methylcoumarin can inhibit the growth of S. aureus and the growth of Gram-positive bacteria within a concentration of 0.8–3.6 μg/ml, and also has a strong hepatoprotective activity. |
||
S5008 |
Ciprofloxacin hydrochlorideCiprofloxacin (CPX, Cetraxal, Ciloxan, Cipro, Bay-09867) hydrochloride, a fluorinated quinolone, is a β-diketone antibiotic with a broad spectrum antibacterial activity. Ciprofloxacin is an inhibitor of bacterial DNA gyrase (a subclass of Type II topoisomerases). |
||
S3496 |
Lefamulin acetate (Xenleta)Lefamulin acetate (Xenleta, BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, thus preventing the binding of transfer RNA for peptide transfer. |
||
S4941 |
FarnesolFarnesol is a natural sesquiterpene alcohol that is potent in treating antimetabolic disorders, anti-inflammation, showing antioxidant, anticancer, and antibiotic effects. |
||
S6584 |
AmdinocillinAmdinocillin (Mecillinam, Coactin, FL 1060) is a β-lactam antibiotic with a broad spectrum of antibacterial activity. Amdinocillin is active alone against many gram-negative organisms. |
||
S4425 |
Rifamycin SRifamycin S, a quinone and an antibiotic against Gram-positive bacteria (including MRSA), is a clinical drug used to treat tuberculosis and leprosy. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation. |
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S4436 |
PleuromutilinPleuromutilin (Drosophilin B, Mutilin 14-glycolate), the lead compound for novel antibiotics, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria. |
||
S7419 |
Blasticidin S HClBlasticidin S HCl is a nucleoside antibiotic isolated from Stretomyces girseochromogenes, and acts as a DNA and protein synthesis inhibitor, used to select transfected cells carrying bsr or BSD resistance genes. |
||
S4488 |
Delafloxacin MeglumineDelafloxacin (ABT-492, RX-3341, WQ-3034, Baxdela) meglumine is a broad-spectrum fluoroquinolone antibiotic against multiple pathogens. |
||
S5968 |
Kasugamycin hydrochloride hydrateKasugamycin (Ksg) hydrochloride hydrate, an antibiotic which binds both the 30S and 70S ribosome, specifically inhibits translation initiation of canonical but not of leaderless messenger RNAs. |
||
S5294 |
Cephalotin acidCephalotin acid (Cephalothin, Cefalotin, Cephalothinum) is a cephalosporin antibiotic. |
||
S2385 |
HordenineHordenine (N,N-dimethyl-4-hydroxyphenylethylamine) is a phenylethylamine alkaloid with antibacterial and antibiotic properties. |
||
S5417 |
Spectinomycin dihydrochloride pentahydrateSpectinomycin dihydrochloride pentahydrate (Trobicin) is a widely used antibiotic that inhibits bacterial protein synthesis by blocking translocation of messenger RNA and transfer RNAs on the ribosome. |
||
S6562 |
KKL-35KKL-35 inhibits the trans-translation tagging reaction with an IC50 of 0.9 µM. It has broad-spectrum antibiotic activity. |
||
S5330 |
Amikacin Sulfate SaltAmikacin (BAY 41-6551) sulfate, a semisynthetic analog of kanamycin, is an aminoglycoside antibiotic which is very active against most gram-negative bacteria including gentamicin- and tobramycin-resistant strains. |
||
S1450 |
NanchangmycinNanchangmycin is a polyether antibiotic with similar structure to dianemycin and is very active against a broad spectrum of harmful nematodes and insects but not for mammals and plants. |
Catalog No. | Information | Product Use Citations | Product Validations |
---|---|---|---|
S7046 |
Brefeldin ABrefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells, induces cancer cell differentiation and apoptosis. It could also improve the HDR(homology-directed repair) efficiency and be an enhancer of CRISPR-mediated HDR. Brefeldin A is also an inhibitor of autophagy and mitophagy. |
![]() ![]() Cells were treated with brefeldin A or manumycin A, and the resulting supernatant was collected after 48 h for exosomal preparation (lanes 1 and 2), or exosomes obtained from C81 cells were trypsin-treated or freeze/thawed (F/T) and then trypsin-treated (lanes 3 and 4). Lanes 5 and 6, input exosome controls from C81 or CEM cells, respectively. Resulting exosomes were assayed for the presence of Tax by Western blotting. |
|
S4974 |
Oxacillin sodiumOxacillin sodium (salt) is a narrow-spectrum β-lactam antibiotic that can be used for treatment of methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia. |
||
S5199 |
Oxytetracycline hydrochlorideOxytetracycline (OTC, Oxycycin, Stevacin, Terramycin) hydrochloride is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins. |
||
S4490 |
TetracyclineTetracycline (TC) is a broad-spectrum antibiotic that exhibits activity against a wide range of microorganisms including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, rickettsiae, and protozoan parasites. |
||
S4979 |
Procaine penicillin GPenicillin G Procaine (PGP, Penicillin G Procaine, Bicillin C-R), a crystalline complex combining penicillin G with procaine, is a β-lactam antibiotic. |
||
E0706New |
Gemifloxacin mesylateGemifloxacin mesylate (SB265805 mesylate; LB20304 mesylate) is a novel fluoronaphthyridone with a broad spectrum of antimicrobial activity and enhances activity against gram-positive aerobes. |
||
E0656New |
7-Methylcoumarin7-Methylcoumarin can inhibit the growth of S. aureus and the growth of Gram-positive bacteria within a concentration of 0.8–3.6 μg/ml, and also has a strong hepatoprotective activity. |
||
S5008 |
Ciprofloxacin hydrochlorideCiprofloxacin (CPX, Cetraxal, Ciloxan, Cipro, Bay-09867) hydrochloride, a fluorinated quinolone, is a β-diketone antibiotic with a broad spectrum antibacterial activity. Ciprofloxacin is an inhibitor of bacterial DNA gyrase (a subclass of Type II topoisomerases). |
||
S3496 |
Lefamulin acetate (Xenleta)Lefamulin acetate (Xenleta, BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, thus preventing the binding of transfer RNA for peptide transfer. |
||
S4941 |
FarnesolFarnesol is a natural sesquiterpene alcohol that is potent in treating antimetabolic disorders, anti-inflammation, showing antioxidant, anticancer, and antibiotic effects. |
||
S6584 |
AmdinocillinAmdinocillin (Mecillinam, Coactin, FL 1060) is a β-lactam antibiotic with a broad spectrum of antibacterial activity. Amdinocillin is active alone against many gram-negative organisms. |
||
S4425 |
Rifamycin SRifamycin S, a quinone and an antibiotic against Gram-positive bacteria (including MRSA), is a clinical drug used to treat tuberculosis and leprosy. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation. |
||
S4436 |
PleuromutilinPleuromutilin (Drosophilin B, Mutilin 14-glycolate), the lead compound for novel antibiotics, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria. |
||
S7419 |
Blasticidin S HClBlasticidin S HCl is a nucleoside antibiotic isolated from Stretomyces girseochromogenes, and acts as a DNA and protein synthesis inhibitor, used to select transfected cells carrying bsr or BSD resistance genes. |
||
S4488 |
Delafloxacin MeglumineDelafloxacin (ABT-492, RX-3341, WQ-3034, Baxdela) meglumine is a broad-spectrum fluoroquinolone antibiotic against multiple pathogens. |
Catalog No. | Information | Product Use Citations | Product Validations |
---|---|---|---|
S5968 |
Kasugamycin hydrochloride hydrateKasugamycin (Ksg) hydrochloride hydrate, an antibiotic which binds both the 30S and 70S ribosome, specifically inhibits translation initiation of canonical but not of leaderless messenger RNAs. |
||
S5294 |
Cephalotin acidCephalotin acid (Cephalothin, Cefalotin, Cephalothinum) is a cephalosporin antibiotic. |
||
S2385 |
HordenineHordenine (N,N-dimethyl-4-hydroxyphenylethylamine) is a phenylethylamine alkaloid with antibacterial and antibiotic properties. |
||
S5417 |
Spectinomycin dihydrochloride pentahydrateSpectinomycin dihydrochloride pentahydrate (Trobicin) is a widely used antibiotic that inhibits bacterial protein synthesis by blocking translocation of messenger RNA and transfer RNAs on the ribosome. |
||
S6562 |
KKL-35KKL-35 inhibits the trans-translation tagging reaction with an IC50 of 0.9 µM. It has broad-spectrum antibiotic activity. |
||
S5330 |
Amikacin Sulfate SaltAmikacin (BAY 41-6551) sulfate, a semisynthetic analog of kanamycin, is an aminoglycoside antibiotic which is very active against most gram-negative bacteria including gentamicin- and tobramycin-resistant strains. |
||
S1450 |
NanchangmycinNanchangmycin is a polyether antibiotic with similar structure to dianemycin and is very active against a broad spectrum of harmful nematodes and insects but not for mammals and plants. |