BACE
Inhibitory Selectivity
BACE Products
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S2156 |
LY2886721LY2886721 is a BACE inhibitor used for the treatment of Alzheimer's Disease. Phase 1/2. |
|
|
| S3245 |
NodakenetinNodakenetin (NANI), a plant-derived coumarin isolated from Angelica decursiva, inhibits α-glucosidase, PTP1B, rat lens aldose reductase (RLAR), AChE, BChE, and β-site amyloid precursor protein cleaving enzyme 1 (BACE1). Nodakenetin alters the protein expression of Bax and Bcl-2, and prompts mitochondrial apoptosis. Nodakenetin exhibits anti-tumor activity. |
||
| S6503 |
LX2343LX2343 is a multi-target agent that exhibits a high capability for ameliorating multi-abnormalities of AD pathogenesis. It is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM. |
||
| S3326New |
Phytic acid dipotassium saltPhytic acid dipotassium salt (Phytic acid potassium, IP6 (PS)), an endogenous metabolite in rice grain extract and digest, inhibits β-secretase 1 (BACE1) with IC50 of approximately 0.25 μM. |
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S2156 |
LY2886721LY2886721 is a BACE inhibitor used for the treatment of Alzheimer's Disease. Phase 1/2. |
|
|
| S3245 |
NodakenetinNodakenetin (NANI), a plant-derived coumarin isolated from Angelica decursiva, inhibits α-glucosidase, PTP1B, rat lens aldose reductase (RLAR), AChE, BChE, and β-site amyloid precursor protein cleaving enzyme 1 (BACE1). Nodakenetin alters the protein expression of Bax and Bcl-2, and prompts mitochondrial apoptosis. Nodakenetin exhibits anti-tumor activity. |
||
| S6503 |
LX2343LX2343 is a multi-target agent that exhibits a high capability for ameliorating multi-abnormalities of AD pathogenesis. It is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM. |
||
| S3326New |
Phytic acid dipotassium saltPhytic acid dipotassium salt (Phytic acid potassium, IP6 (PS)), an endogenous metabolite in rice grain extract and digest, inhibits β-secretase 1 (BACE1) with IC50 of approximately 0.25 μM. |
