Epoxide Hydrolase

Inhibitory Selectivity

Isoform-specific Inhibitors

Epoxide Hydrolase Products

New Epoxide Hydrolase Products
Catalog No. Information Product Use Citations Product Validations
E0473New

CUDA

CUDA is a potent inhibitor of soluble epoxide hydrolase (sEH), with IC50s of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively, also selectively increases peroxisome proliferator-activated receptor (PPAR) alpha activity.

S0752

AUDA

AUDA (compound 43) is a potent inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 18 nM and 69 nM for the mouse sEH and human sEH, respectively. AUDA has anti-inflammatory activity that reduces the protein expression of MMP-9, IL-1β, TNF-α and TGF-β. AUDA downregulates Smad3 and p38 signaling pathways.

S0548

1-Cyclohexyl-3-dodecyl urea

1-Cyclohexyl-3-dodecyl urea (CDU, N-Cyclohexyl-N-dodecyl urea, NCND) is a highly selective inhibitor of soluble epoxide hydrolase (sEH) that increases epoxyeicosatrienoic acids (EETs) levels.

E2847New

TPPU

TPPU is a soluble epoxide hydrolase (sEH) inhibitor with IC50 values of 37 and 3.7 nM for monkey and human sEH, respectively.

Catalog No. Information Product Use Citations Product Validations
E0473New

CUDA

CUDA is a potent inhibitor of soluble epoxide hydrolase (sEH), with IC50s of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively, also selectively increases peroxisome proliferator-activated receptor (PPAR) alpha activity.

S0752

AUDA

AUDA (compound 43) is a potent inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 18 nM and 69 nM for the mouse sEH and human sEH, respectively. AUDA has anti-inflammatory activity that reduces the protein expression of MMP-9, IL-1β, TNF-α and TGF-β. AUDA downregulates Smad3 and p38 signaling pathways.

S0548

1-Cyclohexyl-3-dodecyl urea

1-Cyclohexyl-3-dodecyl urea (CDU, N-Cyclohexyl-N-dodecyl urea, NCND) is a highly selective inhibitor of soluble epoxide hydrolase (sEH) that increases epoxyeicosatrienoic acids (EETs) levels.

E2847New

TPPU

TPPU is a soluble epoxide hydrolase (sEH) inhibitor with IC50 values of 37 and 3.7 nM for monkey and human sEH, respectively.