FTO

Inhibitory Selectivity

FTO Products

New FTO Products
Catalog No. Information Product Use Citations Product Validations
S8837

FB23-2

FB23-2 is a potent and selective FTO inhibitor that directly binds to FTO and selectively inhibits FTO's N6-methyladenosine (m6A) demethylase activity with IC50 of 2.6 μM.

S2400

Rheic Acid

Rhein (Monorhein, NSC 38629, Rheinic) is an anthraquinone compound enriched in the fresh rhizome of Rheum coreanum Nakai, showing anti-inflammation and antitumor activities. Rhein is an FTO (mRNA N6-methyladenine demethylase) inhibitor and also inhibits AlkB repair enzymes.

S9876New

Dac51

Dac51 is a potent FTO inhibitor with an IC50 of 0.4 μM for inhibiting FTO demethylation.

S6291New

FB23

FB23 is a potent and selective inhibitor of FTO demethylase with IC50 of 60 nM. FB23 directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity.

Catalog No. Information Product Use Citations Product Validations
S8837

FB23-2

FB23-2 is a potent and selective FTO inhibitor that directly binds to FTO and selectively inhibits FTO's N6-methyladenosine (m6A) demethylase activity with IC50 of 2.6 μM.

S2400

Rheic Acid

Rhein (Monorhein, NSC 38629, Rheinic) is an anthraquinone compound enriched in the fresh rhizome of Rheum coreanum Nakai, showing anti-inflammation and antitumor activities. Rhein is an FTO (mRNA N6-methyladenine demethylase) inhibitor and also inhibits AlkB repair enzymes.

S9876New

Dac51

Dac51 is a potent FTO inhibitor with an IC50 of 0.4 μM for inhibiting FTO demethylation.

S6291New

FB23

FB23 is a potent and selective inhibitor of FTO demethylase with IC50 of 60 nM. FB23 directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity.