FTO
Inhibitory Selectivity
FTO Products
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S8837 |
FB23-2FB23-2 is a potent and selective FTO inhibitor that directly binds to FTO and selectively inhibits FTO's N6-methyladenosine (m6A) demethylase activity with IC50 of 2.6 μM. |
||
| S2400 |
Rheic AcidRhein (Monorhein, NSC 38629, Rheinic) is an anthraquinone compound enriched in the fresh rhizome of Rheum coreanum Nakai, showing anti-inflammation and antitumor activities. Rhein is an FTO (mRNA N6-methyladenine demethylase) inhibitor and also inhibits AlkB repair enzymes. |
||
| S9876New |
Dac51Dac51 is a potent FTO inhibitor with an IC50 of 0.4 μM for inhibiting FTO demethylation. |
||
| S6291New |
FB23FB23 is a potent and selective inhibitor of FTO demethylase with IC50 of 60 nM. FB23 directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity. |
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S8837 |
FB23-2FB23-2 is a potent and selective FTO inhibitor that directly binds to FTO and selectively inhibits FTO's N6-methyladenosine (m6A) demethylase activity with IC50 of 2.6 μM. |
||
| S2400 |
Rheic AcidRhein (Monorhein, NSC 38629, Rheinic) is an anthraquinone compound enriched in the fresh rhizome of Rheum coreanum Nakai, showing anti-inflammation and antitumor activities. Rhein is an FTO (mRNA N6-methyladenine demethylase) inhibitor and also inhibits AlkB repair enzymes. |
||
| S9876New |
Dac51Dac51 is a potent FTO inhibitor with an IC50 of 0.4 μM for inhibiting FTO demethylation. |
||
| S6291New |
FB23FB23 is a potent and selective inhibitor of FTO demethylase with IC50 of 60 nM. FB23 directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity. |
