Glucosylceramide Synthase

Inhibitory Selectivity

Glucosylceramide Synthase Products

New Glucosylceramide Synthase Products
Catalog No. Information Product Use Citations Product Validations
S4433

Eliglustat hemitartrate

Eliglustat hemitartrate (Genz-112638, Eliglustat tartrate) is a potent, specific and orally active inhibitor of glucosylceramide synthase with IC50 of 24 nM.

E0646New

Ibiglustat succinate

Ibiglustat succinate (Venglustat succinate) is a glucosylceramide (GlcCer) synthase inhibitor that blocks the formation of glucosylceramide.

E0786New

N-Desmethyltamoxifen

N-Desmethyltamoxifen, the major metabolite of Tamoxifen in humans and a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen, also is a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation.

Catalog No. Information Product Use Citations Product Validations
S4433

Eliglustat hemitartrate

Eliglustat hemitartrate (Genz-112638, Eliglustat tartrate) is a potent, specific and orally active inhibitor of glucosylceramide synthase with IC50 of 24 nM.

E0646New

Ibiglustat succinate

Ibiglustat succinate (Venglustat succinate) is a glucosylceramide (GlcCer) synthase inhibitor that blocks the formation of glucosylceramide.

Catalog No. Information Product Use Citations Product Validations
E0786New

N-Desmethyltamoxifen

N-Desmethyltamoxifen, the major metabolite of Tamoxifen in humans and a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen, also is a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation.