NAMPT

Inhibitory Selectivity

NAMPT Products

New NAMPT Products
Catalog No. Information Product Use Citations Product Validations
S7316

STF-118804

STF-118804 is a highly specific NAMPT inhibitor.

S6629

GNE-617

GNE-617 is a highly potent inhibitor of NAMPT activity with an IC50 of 5 nM.

S8444

KPT 9274 ( ATG-019)

KPT 9274 ( ATG-019) is an orally bioavailable small molecule that is a non-competitive dual inhibitor of PAK4 and NAMPT. It shows an IC50 of ~120 nM for NAMPT in a cell-free enzymatic assay.

S8117

GMX1778 (CHS828)

GMX1778 (CHS828) is a potent and specific inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) with IC50 and Kd of < 25 nM and 120 nM, respectively. GMX1778 induces programmed cell death with apoptotic features. Phase 1.

S9706New

OT-82

OT-82 is a novel nicotinamide phosphoribosyltransferase (NAMPT) inhibitor with average IC50s of 13.03   nM in non-HP cancer cells and 2.89   nM in HP cancer cells, respectively.

S7968

P7C3

P7C3 is a potent proneurogenic and neuroprotective chemical that targets NAMPT enzyme.

S8980

SBI-797812

SBI-797812 is a NAMPT activator which is structurally similar to active-site directed NAMPT inhibitors and blocks binding of these inhibitors to NAMPT. SBI-797812 turns NAMPT into a "super catalyst" that more efficiently generates NMN.

Catalog No. Information Product Use Citations Product Validations
S7316

STF-118804

STF-118804 is a highly specific NAMPT inhibitor.

S6629

GNE-617

GNE-617 is a highly potent inhibitor of NAMPT activity with an IC50 of 5 nM.

S8444

KPT 9274 ( ATG-019)

KPT 9274 ( ATG-019) is an orally bioavailable small molecule that is a non-competitive dual inhibitor of PAK4 and NAMPT. It shows an IC50 of ~120 nM for NAMPT in a cell-free enzymatic assay.

S8117

GMX1778 (CHS828)

GMX1778 (CHS828) is a potent and specific inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) with IC50 and Kd of < 25 nM and 120 nM, respectively. GMX1778 induces programmed cell death with apoptotic features. Phase 1.

S9706New

OT-82

OT-82 is a novel nicotinamide phosphoribosyltransferase (NAMPT) inhibitor with average IC50s of 13.03   nM in non-HP cancer cells and 2.89   nM in HP cancer cells, respectively.

Catalog No. Information Product Use Citations Product Validations
S7968

P7C3

P7C3 is a potent proneurogenic and neuroprotective chemical that targets NAMPT enzyme.

S8980

SBI-797812

SBI-797812 is a NAMPT activator which is structurally similar to active-site directed NAMPT inhibitors and blocks binding of these inhibitors to NAMPT. SBI-797812 turns NAMPT into a "super catalyst" that more efficiently generates NMN.