Pyroptosis
Inhibitory Selectivity
Pyroptosis Products
Catalog No. | Information | Product Use Citations | Product Validations |
---|---|---|---|
S9817 |
Ac-FLTD-CMKAc-FLTD-CMK is a specific inhibitor for inflammatory caspases. Ac-FLTD-CMK inhibits gasdermin D (GSDMD) cleavage by caspases-1, -4, -5, and -11 in vitro. Ac-FLTD-CMK is effective against caspases-1, caspases-4 and caspases-5 with IC50 of 46.7 nM, 1.49 μM and 329 nM, respectively. |
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S5465 |
MorronisideMorroniside, an iridoid glycoside, is the main active ingredient from Cornus officinalis Sieb. et Zucc. and Sambucus williamsii Hance. It has therapeutic effects on diabetic angiopathies, renal damage, lipid metabolism and inflammation and bone resorption. Morroniside has neuroprotective effect by inhibiting neuron apoptosis and MMP2/9 expression. |
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S9302 |
Polyphyllin VIPolyphyllin VI derived from Paris polyphylla possess anti-cancer activities. |
Catalog No. | Information | Product Use Citations | Product Validations |
---|---|---|---|
S9817 |
Ac-FLTD-CMKAc-FLTD-CMK is a specific inhibitor for inflammatory caspases. Ac-FLTD-CMK inhibits gasdermin D (GSDMD) cleavage by caspases-1, -4, -5, and -11 in vitro. Ac-FLTD-CMK is effective against caspases-1, caspases-4 and caspases-5 with IC50 of 46.7 nM, 1.49 μM and 329 nM, respectively. |
||
S5465 |
MorronisideMorroniside, an iridoid glycoside, is the main active ingredient from Cornus officinalis Sieb. et Zucc. and Sambucus williamsii Hance. It has therapeutic effects on diabetic angiopathies, renal damage, lipid metabolism and inflammation and bone resorption. Morroniside has neuroprotective effect by inhibiting neuron apoptosis and MMP2/9 expression. |
Catalog No. | Information | Product Use Citations | Product Validations |
---|---|---|---|
S9302 |
Polyphyllin VIPolyphyllin VI derived from Paris polyphylla possess anti-cancer activities. |