Retinoid Receptor Activation | Retinoid Receptor Agonist Review

Inhibitory Selectivity

Isoform-specific Inhibitors

Retinoid Receptor Products

All (4) Retinoid Receptor Antagonists (1) Retinoid Receptor Agonists (3)

Catalog No.	Information	Product Use Citations
S6605	AR7 AR7 is a retinoic acid receptor α (RARα) antagonist.
S4627	TTNPB (Arotinoid Acid) TTNPB (Arotinoid Acid, Ro 13-7410, AGN-191183) is a potent RAR agonist, and inhibits binding of [³H]tRA with IC50 of 5.1 nM, 4.5 nM, and 9.3 nM for human RARα, β, and γ, respectively.	Int J Mol Sci, 2022, 23(8)4213 Cell Signal, 2022, 93:110304 Sci Rep, 2021, 11(1):10931
S6132	All trans-Retinal All trans-Retinal (Retinaldehyde, Vitamin A aldehyde, Retinene), a component of the retinoid cycle, is converted to retinoic acid in vivo by the action of retinal dehydrogenase. Retinoic acid is a ligand for both RAR and RXR. All trans-retinal ias a potent photosensitizer.
S2933	AM580 AM580 is a retinoic acid receptor agonist with Kd values of 8 nM, 131 nM and 450 nM for RARα, RARβ and RARγ.	Cell Res, 2022, 10.1038/s41422-022-00668-0 J Leukoc Biol, 2022, 111(5):1107-1121 Stem Cells Int, 2018, 2018:5965727

Catalog No.

Information

Product Use Citations

Product Validations

S6605

AR7

AR7 is a retinoic acid receptor α (RARα) antagonist.

Catalog No.	Information	Product Use Citations
S4627	TTNPB (Arotinoid Acid) TTNPB (Arotinoid Acid, Ro 13-7410, AGN-191183) is a potent RAR agonist, and inhibits binding of [³H]tRA with IC50 of 5.1 nM, 4.5 nM, and 9.3 nM for human RARα, β, and γ, respectively.	Int J Mol Sci, 2022, 23(8)4213 Cell Signal, 2022, 93:110304 Sci Rep, 2021, 11(1):10931
S6132	All trans-Retinal All trans-Retinal (Retinaldehyde, Vitamin A aldehyde, Retinene), a component of the retinoid cycle, is converted to retinoic acid in vivo by the action of retinal dehydrogenase. Retinoic acid is a ligand for both RAR and RXR. All trans-retinal ias a potent photosensitizer.
S2933	AM580 AM580 is a retinoic acid receptor agonist with Kd values of 8 nM, 131 nM and 450 nM for RARα, RARβ and RARγ.	Cell Res, 2022, 10.1038/s41422-022-00668-0 J Leukoc Biol, 2022, 111(5):1107-1121 Stem Cells Int, 2018, 2018:5965727

Catalog No.

Information

Product Use Citations

Product Validations

S4627

TTNPB (Arotinoid Acid)

TTNPB (Arotinoid Acid, Ro 13-7410, AGN-191183) is a potent RAR agonist, and inhibits binding of [³H]tRA with IC50 of 5.1 nM, 4.5 nM, and 9.3 nM for human RARα, β, and γ, respectively.

Int J Mol Sci, 2022, 23(8)4213

Cell Signal, 2022, 93:110304

Sci Rep, 2021, 11(1):10931

S6132

All trans-Retinal (Retinaldehyde, Vitamin A aldehyde, Retinene), a component of the retinoid cycle, is converted to retinoic acid in vivo by the action of retinal dehydrogenase. Retinoic acid is a ligand for both RAR and RXR. All trans-retinal ias a potent photosensitizer.

S2933