γGCS
Inhibitory Selectivity
γGCS Products
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S9728 |
BSO (L-Buthionine-(S,R)-sulfoximine)BSO (L-Buthionine-(S,R)-sulfoximine, L-Buthionine sulfoximine, l-BSO) is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase (γ-glutamylcysteine synthetase, γ-GCS) and depletes cellular glutathione levels. The IC50 of BSO on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively. |
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S9728 |
BSO (L-Buthionine-(S,R)-sulfoximine)BSO (L-Buthionine-(S,R)-sulfoximine, L-Buthionine sulfoximine, l-BSO) is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase (γ-glutamylcysteine synthetase, γ-GCS) and depletes cellular glutathione levels. The IC50 of BSO on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively. |
