SREBP
Inhibitory Selectivity
SREBP Products
Catalog No. | Information | Product Use Citations | Product Validations |
---|---|---|---|
S8284 |
Fatostatin (125B11) HBrFatostatin HBr (Fatostatin A, 125B11) is an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2. |
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S9067 |
PseudoprotodioscinPseudoprotodioscin is a steroidal saponin from plants and exhibits anti-inflammatory and anticancer activities. Pseudoprotodioscin inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides. |
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S9785 |
FatostatinFatostatin (125B11), a diarylthiazole derivative, is a specific inhibitor of Sterol regulatory element binding proteins (SREBPs) activation. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin suppresses growth and enhances apoptosis in cancer cells. |
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E0209New |
CinobufotalinCinobufotalin, extracted from the skin secretion of the giant toad, is a novel SREBP1 inhibitor that suppresses proliferation of hepatocellular carcinoma by targeting lipogenesis. |
Catalog No. | Information | Product Use Citations | Product Validations |
---|---|---|---|
S8284 |
Fatostatin (125B11) HBrFatostatin HBr (Fatostatin A, 125B11) is an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2. |
||
S9067 |
PseudoprotodioscinPseudoprotodioscin is a steroidal saponin from plants and exhibits anti-inflammatory and anticancer activities. Pseudoprotodioscin inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides. |
||
S9785 |
FatostatinFatostatin (125B11), a diarylthiazole derivative, is a specific inhibitor of Sterol regulatory element binding proteins (SREBPs) activation. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin suppresses growth and enhances apoptosis in cancer cells. |
||
E0209New |
CinobufotalinCinobufotalin, extracted from the skin secretion of the giant toad, is a novel SREBP1 inhibitor that suppresses proliferation of hepatocellular carcinoma by targeting lipogenesis. |