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Wee1

Inhibitory Selectivity

Wee1 Products

All (1) Wee1 Inhibitors (1)

Catalog No.

Information

Product Use Citations

Product Validations

S8148

PD0166285

PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations (IC50=24 nM for Wee1 and 72 nM for Myt1). PD0166285 is also a novel G2 checkpoint abrogator. PD0166285 induces apoptosis.

Cancer Sci, 2020, 112(1):133-143

Nature, 2019, 10.1038/s41586-019-1607-3

Nature, 2019, 574(7777):268-272

Catalog No.

Information

Product Use Citations

Product Validations

S8148

PD0166285

PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations (IC50=24 nM for Wee1 and 72 nM for Myt1). PD0166285 is also a novel G2 checkpoint abrogator. PD0166285 induces apoptosis.

Cancer Sci, 2020, 112(1):133-143

Nature, 2019, 10.1038/s41586-019-1607-3

Nature, 2019, 574(7777):268-272

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